Reverse complementary matches simultaneously promote both back-splicing and exon-skipping
Abstract Background Circular RNAs (circRNAs) play diverse roles in different biological and physiological environments and are always expressed in a tissue-specific manner.Especially, circRNAs are enriched in the brain tissues of almost all investigated species, including humans, mice, Drosophila, etc.Although circRNAs were found in C.elegans, the